Acetylation dependent functions of Rab22a-NeoF1 Fusion Protein in Osteosarcoma

Background: Rab22a-NeoF1 fusion gene containing the 1-38aa of Rab22a (Rab22a(1-38)) plays a decisive role in driving tumor metastasis by activating RhoA via binding to SmgGDS607. However, its intercellular regulation remains unknown. Methods: The Lys7 (K7) acetylation of Rab22a-NeoF1 was initially i...

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Publicado en:Theranostics
Autores principales: Liang, Xiaoting, Wang, Xin, He, Yaohui, Wu, Yuanzhong, Zhong, Li, Liu, Wen, Liao, Dan, Kang, Tiebang
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2020
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359080/
https://ncbi.nlm.nih.gov/pubmed/32685017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46082
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