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IMMUNEPOTENT CRP induces DAMPS release and ROS-dependent autophagosome formation in HeLa and MCF-7 cells

BACKGROUND: IMMUNEPOTENT CRP (ICRP) can be cytotoxic to cancer cell lines. However, its widespread use in cancer patients has been limited by the absence of conclusive data on the molecular mechanism of its action. Here, we evaluated the mechanism of cell death induced by ICRP in HeLa and MCF-7 cell...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Martínez-Torres, Ana Carolina, Reyes-Ruiz, Alejandra, Calvillo-Rodriguez, Kenny Misael, Alvarez-Valadez, Karla Maria, Uscanga-Palomeque, Ashanti C., Tamez-Guerra, Reyes S., Rodríguez-Padilla, Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359018/
https://ncbi.nlm.nih.gov/pubmed/32660440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07124-5
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