IMMUNEPOTENT CRP induces DAMPS release and ROS-dependent autophagosome formation in HeLa and MCF-7 cells

BACKGROUND: IMMUNEPOTENT CRP (ICRP) can be cytotoxic to cancer cell lines. However, its widespread use in cancer patients has been limited by the absence of conclusive data on the molecular mechanism of its action. Here, we evaluated the mechanism of cell death induced by ICRP in HeLa and MCF-7 cell...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Martínez-Torres, Ana Carolina, Reyes-Ruiz, Alejandra, Calvillo-Rodriguez, Kenny Misael, Alvarez-Valadez, Karla Maria, Uscanga-Palomeque, Ashanti C., Tamez-Guerra, Reyes S., Rodríguez-Padilla, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359018/
https://ncbi.nlm.nih.gov/pubmed/32660440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07124-5
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