Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells

Calcific aortic valve disease (CAVD) occurs via a pathophysiological process that includes inflammation-induced osteoblastic differentiation of aortic valvular interstitial cells (AVICs). Here, we investigated the role of the anti-inflammatory compound caffeic acid phenethyl ester (CAPE) in inhibiti...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Liu, Ming, Li, Fei, Huang, Yuming, Zhou, Tingwen, Chen, Si, Li, Geng, Shi, Jiawei, Dong, Nianguo, Xu, Kang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358518/
https://ncbi.nlm.nih.gov/pubmed/32733235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00826
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares