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Transient Chimeric Ad5/37 Fiber Enhances NK-92 Carrier Cell-Mediated Delivery of Oncolytic Adenovirus Type 5 to Tumor Cells

Methods for customizing and improving virus vector tropism are limited. In this study, we introduce a microRNA (miRNA)-regulated molecular method to enhance vector transduction without genome alteration. Based on the importance of adenovirus (Ad) vectors for cancer and gene treatment, we exemplified...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Gao, Jian, Zhang, Wenli, Mese, Kemal, Bunz, Oskar, Lu, Fengmin, Ehrhardt, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358217/
https://ncbi.nlm.nih.gov/pubmed/32695840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.06.010
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