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Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches
Protein conformational switches or allosteric proteins play a key role in the regulation of many essential biological pathways. Nonetheless, the implementation of protein conformational switches in protein design applications has proven challenging, with only a few known examples that are not deriva...
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| 發表在: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7358038/ https://ncbi.nlm.nih.gov/pubmed/31557439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b04664 |
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