Pharmacokinetics of high-dose tigecycline in critically ill patients with severe infections

BACKGROUND: In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective observational study to describe the pharmacokinetic/pharmacodynamic (PK/PD) pro...

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Dades bibliogràfiques
Publicat a:Ann Intensive Care
Autors principals: De Pascale, Gennaro, Lisi, Lucia, Ciotti, Gabriella Maria Pia, Vallecoccia, Maria Sole, Cutuli, Salvatore Lucio, Cascarano, Laura, Gelormini, Camilla, Bello, Giuseppe, Montini, Luca, Carelli, Simone, Di Gravio, Valentina, Tumbarello, Mario, Sanguinetti, Maurizio, Navarra, Pierluigi, Antonelli, Massimo
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357259/
https://ncbi.nlm.nih.gov/pubmed/32661791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-020-00715-2
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