Pharmacokinetics of high-dose tigecycline in critically ill patients with severe infections

BACKGROUND: In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective observational study to describe the pharmacokinetic/pharmacodynamic (PK/PD) pro...

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Detalhes bibliográficos
Publicado no:Ann Intensive Care
Main Authors: De Pascale, Gennaro, Lisi, Lucia, Ciotti, Gabriella Maria Pia, Vallecoccia, Maria Sole, Cutuli, Salvatore Lucio, Cascarano, Laura, Gelormini, Camilla, Bello, Giuseppe, Montini, Luca, Carelli, Simone, Di Gravio, Valentina, Tumbarello, Mario, Sanguinetti, Maurizio, Navarra, Pierluigi, Antonelli, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357259/
https://ncbi.nlm.nih.gov/pubmed/32661791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-020-00715-2
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