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Aging, inflammation, and HSC
In this issue of Blood, He et al show that a tumor necrosis factor α (TNFα)-mediated pathway regulating interleukin-27 receptor subunit α (IL-27Ra) expression on hematopoietic stem cells (HSCs) mediates changes in HSCs that occur in old age, including myeloid skewing, reduced reconstitution potentia...
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| Published in: | Blood |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7357189/ https://ncbi.nlm.nih.gov/pubmed/32645167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006070 |
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