Subcutaneous Administration of Apolipoprotein J-Derived Mimetic Peptide d-[113–122]apoJ Improves LDL and HDL Function and Prevents Atherosclerosis in LDLR-KO Mice

Mimetic peptides are potential therapeutic agents for atherosclerosis. d-[113–122]apolipoprotein (apo) J (d-[113–122]apoJ) is a 10-residue peptide that is predicted to form a class G* amphipathic helix 6 from apoJ; it shows anti-inflammatory and anti-atherogenic properties. In the present study, we...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Rivas-Urbina, Andrea, Rull, Anna, Aldana-Ramos, Joile, Santos, David, Puig, Nuria, Farre-Cabrerizo, Nuria, Benitez, Sonia, Perez, Antonio, de Gonzalo-Calvo, David, Escola-Gil, Joan Carles, Julve, Josep, Ordoñez-Llanos, Jordi, Sanchez-Quesada, Jose Luis
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356811/
https://ncbi.nlm.nih.gov/pubmed/32485898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060829
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