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Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis

Cerebral β-amyloidosis is a major feature of Alzheimer’s disease (AD), characterized by the accumulation of β-amyloid protein (Aβ) in the brain. Several studies have implicated lipid/lipoprotein metabolism in the regulation of β-amyloidosis. In this regard, HDL (High Density Lipoprotein)-based thera...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fernández-de-Retana, Sofía, Cano-Sarabia, Mary, Marazuela, Paula, Sánchez-Quesada, Jose Luis, Garcia-Leon, Annabel, Montañola, Alex, Montaner, Joan, Maspoch, Daniel, Hernández-Guillamon, Mar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677083/
https://ncbi.nlm.nih.gov/pubmed/29116115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15215-w
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