Against Repurposing Methadone for Glioblastoma Therapy

Methadone, which is used as maintenance medication for outpatient treatment of opioid dependence or as an analgesic drug, has been suggested by preclinical in vitro and mouse studies to induce cell death and sensitivity to chemo- or radiotherapy in leukemia, glioblastoma, and carcinoma cells. These...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Vatter, Tatjana, Klumpp, Lukas, Ganser, Katrin, Stransky, Nicolai, Zips, Daniel, Eckert, Franziska, Huber, Stephan M.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356722/
https://ncbi.nlm.nih.gov/pubmed/32560384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060917
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