Tumoricidal Potential of Novel Amino-1,10-phenanthroline Derived Imine Ligands: Chemical Preparation, Structure, and Biological Investigations

Herein we report the synthesis and structural elucidation of two novel imine-based ligands, 2-(1,10-phenanthrolin-5-yl)imino)methyl)-5-bromophenol (PIB) and N-(1,10-phenanthrolin-5-yl)-1-(thiophen-3-yl)methanimine (PTM) ligands. An in vitro cytotoxicity assay of the synthesized molecules was carried...

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Vydáno v:Molecules
Hlavní autoři: Prasad, Kollur Shiva, Pillai, Renjith Raveendran, Shivamallu, Chandan, Prasad, Shashanka K., Jain, Anisha S., Pradeep, Sushma, Armaković, Stevan, Armaković, Sanja J., Srinivasa, Chandrashekar, Kallimani, Sharadadevi, Amachawadi, Raghavendra G., Ankegowda, Veena Malligere, Marraiki, Najat, Elgorban, Abdallah M., Syed, Asad
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356530/
https://ncbi.nlm.nih.gov/pubmed/32580359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122865
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