Tumoricidal Potential of Novel Amino-1,10-phenanthroline Derived Imine Ligands: Chemical Preparation, Structure, and Biological Investigations

Herein we report the synthesis and structural elucidation of two novel imine-based ligands, 2-(1,10-phenanthrolin-5-yl)imino)methyl)-5-bromophenol (PIB) and N-(1,10-phenanthrolin-5-yl)-1-(thiophen-3-yl)methanimine (PTM) ligands. An in vitro cytotoxicity assay of the synthesized molecules was carried...

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Publicado no:Molecules
Main Authors: Prasad, Kollur Shiva, Pillai, Renjith Raveendran, Shivamallu, Chandan, Prasad, Shashanka K., Jain, Anisha S., Pradeep, Sushma, Armaković, Stevan, Armaković, Sanja J., Srinivasa, Chandrashekar, Kallimani, Sharadadevi, Amachawadi, Raghavendra G., Ankegowda, Veena Malligere, Marraiki, Najat, Elgorban, Abdallah M., Syed, Asad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356530/
https://ncbi.nlm.nih.gov/pubmed/32580359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122865
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