Fabrication of Core Crosslinked Polymeric Micelles as Nanocarriers for Doxorubicin Delivery: Self-Assembly, In Situ Diselenide Metathesis and Redox-Responsive Drug Release

Polymeric micelles (PMs) have been used to improve the poor aqueous solubility, slow absorption and non-selective biodistribution of chemotherapeutic agents (CAs), albeit, they suffer from disassembly and premature release of payloads in the bloodstream. To alleviate the thermodynamic instability of...

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Publicat a:Pharmaceutics
Autors principals: Birhan, Yihenew Simegniew, Darge, Haile Fentahun, Hanurry, Endiries Yibru, Andrgie, Abegaz Tizazu, Mekonnen, Tefera Worku, Chou, Hsiao-Ying, Lai, Juin-Yih, Tsai, Hsieh-Chih
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356386/
https://ncbi.nlm.nih.gov/pubmed/32585885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060580
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