Biotin-Decorated PAMAM G4.5 Dendrimer Nanoparticles to Enhance the Delivery, Anti-Proliferative, and Apoptotic Effects of Chemotherapeutic Drug in Cancer Cells

Biotin receptors are overexpressed by various types of solid cancer cells and play a significant role in tumor metabolism, growth, and metastasis. Thus, targeting the biotin receptors on tumor cells may enhance the efficiency and reduce the side-effects of chemotherapy. The aim of this study was to...

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Publicado en:Pharmaceutics
Main Authors: Hanurry, Endiries Yibru, Mekonnen, Tefera Worku, Andrgie, Abegaz Tizazu, Darge, Haile Fentahun, Birhan, Yihenew Simegniew, Hsu, Wei-Hsin, Chou, Hsiao-Ying, Cheng, Chih-Chia, Lai, Juin-Yih, Tsai, Hsieh-Chih
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7284937/
https://ncbi.nlm.nih.gov/pubmed/32403321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12050443
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