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Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2
While aminoacyl-tRNA synthetase-interacting multifunctional protein 2 (AIMP2) is a tumor suppressor, its exon 2-depleted splice variant (AIMP2-DX2 or shortly DX2) is highly expressed in human lung cancer, and the ratio of DX2 to AIMP2 increases according to the progression of lung cancer. In this st...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7355952/ https://ncbi.nlm.nih.gov/pubmed/32549310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122763 |
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