Tryptophan Metabolism via the Kynurenine Pathway: Implications for Graft Optimization during Machine Perfusion

Access to liver transplantation continues to be hindered by the severe organ shortage. Extended-criteria donor livers could be used to expand the donor pool but are prone to ischemia-reperfusion injury (IRI) and post-transplant graft dysfunction. Ex situ machine perfusion may be used as a platform t...

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Pubblicato in:J Clin Med
Autori principali: Zhang, Anna, Carroll, Cailah, Raigani, Siavash, Karimian, Negin, Huang, Viola, Nagpal, Sonal, Beijert, Irene, Porte, Robert J., Yarmush, Martin, Uygun, Korkut, Yeh, Heidi
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355886/
https://ncbi.nlm.nih.gov/pubmed/32549246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9061864
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