Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies

There continues to be a significant shortage of donor livers for transplantation. One impediment is the discard rate of fatty, or steatotic, livers because of their poor post-transplant function. Steatotic livers are prone to significant ischemia-reperfusion injury (IRI) and data regarding how best...

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Udgivet i:PLoS One
Main Authors: Raigani, Siavash, Karimian, Negin, Huang, Viola, Zhang, Anna M., Beijert, Irene, Geerts, Sharon, Nagpal, Sonal, Hafiz, Ehab O. A., Fontan, Fermin M., Aburawi, Mohamed M., Mahboub, Paria, Markmann, James F., Porte, Robert J., Uygun, Korkut, Yarmush, Martin, Yeh, Heidi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980574/
https://ncbi.nlm.nih.gov/pubmed/31978172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228011
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