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Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies

There continues to be a significant shortage of donor livers for transplantation. One impediment is the discard rate of fatty, or steatotic, livers because of their poor post-transplant function. Steatotic livers are prone to significant ischemia-reperfusion injury (IRI) and data regarding how best...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Raigani, Siavash, Karimian, Negin, Huang, Viola, Zhang, Anna M., Beijert, Irene, Geerts, Sharon, Nagpal, Sonal, Hafiz, Ehab O. A., Fontan, Fermin M., Aburawi, Mohamed M., Mahboub, Paria, Markmann, James F., Porte, Robert J., Uygun, Korkut, Yarmush, Martin, Yeh, Heidi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980574/
https://ncbi.nlm.nih.gov/pubmed/31978172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228011
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