Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies

There continues to be a significant shortage of donor livers for transplantation. One impediment is the discard rate of fatty, or steatotic, livers because of their poor post-transplant function. Steatotic livers are prone to significant ischemia-reperfusion injury (IRI) and data regarding how best...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Raigani, Siavash, Karimian, Negin, Huang, Viola, Zhang, Anna M., Beijert, Irene, Geerts, Sharon, Nagpal, Sonal, Hafiz, Ehab O. A., Fontan, Fermin M., Aburawi, Mohamed M., Mahboub, Paria, Markmann, James F., Porte, Robert J., Uygun, Korkut, Yarmush, Martin, Yeh, Heidi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980574/
https://ncbi.nlm.nih.gov/pubmed/31978172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228011
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