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Design and Characterization of Spray-Dried Chitosan-Naltrexone Microspheres for Microneedle-Assisted Transdermal Delivery

Naltrexone (NTX) hydrochloride is a potent opioid antagonist with significant first-pass metabolism and notable untoward effects when administered orally or intramuscularly. Microneedle (MN)-assisted transdermal delivery is an attractive alternative that can improve therapeutic delivery to deeper sk...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Ogunjimi, Abayomi T., Fiegel, Jennifer, Brogden, Nicole K.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355536/
https://ncbi.nlm.nih.gov/pubmed/32485999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060496
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