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Effect of formulation pH on transport of naltrexone species and pore closure in microneedle-enhanced transdermal drug delivery

Microneedle-enhanced transdermal drug delivery greatly improves the subset of pharmacologically active molecules that can be transported across the skin. Formulation pH plays an important role in all drug delivery systems; however, for transdermal delivery it becomes specifically significant since a...

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Autores principales: Ghosh, Priyanka, Brogden, Nicole K., Stinchcomb, Audra L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718312/
https://ncbi.nlm.nih.gov/pubmed/23590208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3007083
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