A Novel Chemically Differentiated Mouse Embryonic Stem Cell-Based Model to Study Liver Stages of Plasmodium berghei

Asymptomatic and obligatory liver stage (LS) infection of Plasmodium parasites presents an attractive target for antimalarial vaccine and drug development. Lack of robust cellular models to study LS infection has hindered the discovery and validation of host genes essential for intrahepatic parasite...

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Опубликовано в: :Stem Cell Reports
Главные авторы: Tripathi, Jaishree, Segeritz, Charis-Patricia, Griffiths, Gareth, Bushell, Wendy, Vallier, Ludovic, Skarnes, William C., Mota, Maria M., Billker, Oliver
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355138/
https://ncbi.nlm.nih.gov/pubmed/32442532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.04.010
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