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A Novel Chemically Differentiated Mouse Embryonic Stem Cell-Based Model to Study Liver Stages of Plasmodium berghei

Asymptomatic and obligatory liver stage (LS) infection of Plasmodium parasites presents an attractive target for antimalarial vaccine and drug development. Lack of robust cellular models to study LS infection has hindered the discovery and validation of host genes essential for intrahepatic parasite...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tripathi, Jaishree, Segeritz, Charis-Patricia, Griffiths, Gareth, Bushell, Wendy, Vallier, Ludovic, Skarnes, William C., Mota, Maria M., Billker, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355138/
https://ncbi.nlm.nih.gov/pubmed/32442532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.04.010
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