Three types of HLA-G+ extravillous trophoblasts that have distinct immune regulatory properties

During pregnancy, invading HLA-G+ extravillous trophoblasts (EVT) play a key role in placental development, uterine spiral artery remodeling, and prevention of detrimental maternal immune responses to placental and fetal antigens. Failures of these processes are suggested to play a role in the devel...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Papuchova, Henrieta, Kshirsagar, Sarika, Xu, Lily, Bougleux Gomes, Hannah A., Li, Qin, Iyer, Vidya, Norwitz, Errol R., Strominger, Jack L., Tilburgs, Tamara
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355041/
https://ncbi.nlm.nih.gov/pubmed/32581122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000484117
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