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Phase transition of RNA−protein complexes into ordered hollow condensates

Liquid−liquid phase separation of multivalent intrinsically disordered protein−RNA complexes is ubiquitous in both natural and biomimetic systems. So far, isotropic liquid droplets are the most commonly observed topology of RNA−protein condensates in experiments and simulations. Here, by systematica...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Alshareedah, Ibraheem, Moosa, Mahdi Muhammad, Raju, Muralikrishna, Potoyan, Davit A., Banerjee, Priya R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354941/
https://ncbi.nlm.nih.gov/pubmed/32571937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922365117
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