Phase transition of RNA−protein complexes into ordered hollow condensates

Liquid−liquid phase separation of multivalent intrinsically disordered protein−RNA complexes is ubiquitous in both natural and biomimetic systems. So far, isotropic liquid droplets are the most commonly observed topology of RNA−protein condensates in experiments and simulations. Here, by systematica...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Alshareedah, Ibraheem, Moosa, Mahdi Muhammad, Raju, Muralikrishna, Potoyan, Davit A., Banerjee, Priya R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354941/
https://ncbi.nlm.nih.gov/pubmed/32571937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922365117
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