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Muscle‐specific sirtuin1 gain‐of‐function ameliorates skeletal muscle atrophy in a pre‐clinical mouse model of cerebral ischemic stroke

Stroke causes severe long‐term disability in patients due to the induction of skeletal muscle atrophy and weakness, but the molecular mechanisms remain elusive. Using a preclinical mouse model of cerebral ischemic stroke, we show that stroke robustly induced atrophy and significantly decreased SirT1...

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書目詳細資料
發表在:FASEB Bioadv
Main Authors: Tuntevski, Kiril, Hajira, Ameena, Nichols, Austin, Alway, Stephen E., Mohamed, Junaith S.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354693/
https://ncbi.nlm.nih.gov/pubmed/32676579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2020-00017
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