Muscle‐specific sirtuin1 gain‐of‐function ameliorates skeletal muscle atrophy in a pre‐clinical mouse model of cerebral ischemic stroke

Stroke causes severe long‐term disability in patients due to the induction of skeletal muscle atrophy and weakness, but the molecular mechanisms remain elusive. Using a preclinical mouse model of cerebral ischemic stroke, we show that stroke robustly induced atrophy and significantly decreased SirT1...

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Gepubliceerd in:FASEB Bioadv
Hoofdauteurs: Tuntevski, Kiril, Hajira, Ameena, Nichols, Austin, Alway, Stephen E., Mohamed, Junaith S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354693/
https://ncbi.nlm.nih.gov/pubmed/32676579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2020-00017
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