Inhibition of the mitochondrial permeability transition improves bone fracture repair

Bone fracture is accompanied by trauma, mechanical stresses, and inflammation – conditions known to induce the mitochondrial permeability transition. This phenomenon occurs due to opening of the mitochondrial permeability transition pore (MPTP) promoted by cyclophilin D (CypD). MPTP opening leads to...

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Publicado en:Bone
Main Authors: Shares, Brianna H., Smith, Charles O., Sheu, Tzong-Jen, Sautchuk, Rubens, Schilling, Kevin, Shum, Laura C., Paine, Ananta, Huber, Aric, Gira, Emma, Brown, Edward, Awad, Hani, Eliseev, Roman A.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354230/
https://ncbi.nlm.nih.gov/pubmed/32360587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115391
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