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Detecting fitness epistasis in recently admixed populations with genome-wide data

BACKGROUND: Fitness epistasis, the interaction effect of genes at different loci on fitness, makes an important contribution to adaptive evolution. Although fitness interaction evidence has been observed in model organisms, it is more difficult to detect and remains poorly understood in human popula...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Ni, Xumin, Zhou, Mengshi, Wang, Heming, He, Karen Y., Broeckel, Uli, Hanis, Craig, Kardia, Sharon, Redline, Susan, Cooper, Richard S., Tang, Hua, Zhu, Xiaofeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353720/
https://ncbi.nlm.nih.gov/pubmed/32652930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06874-7
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