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Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating disorder characterized by motor neuron apoptosis and subsequent skeletal muscle atrophy caused by oxidative and nitrosative stress, mitochondrial dysfunction, and neuroinflammation. Anthocyanins are polyphenolic compounds found in berries that pos...

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Detaylı Bibliyografya
Yayımlandı:Nutrients
Asıl Yazarlar: Koza, Lilia A., Winter, Aimee N., Holsopple, Jessica, Baybayon-Grandgeorge, Angela N., Pena, Claudia, Olson, Jeffrey R., Mazzarino, Randall C., Patterson, David, Linseman, Daniel A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353311/
https://ncbi.nlm.nih.gov/pubmed/32570926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12061824
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