Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating disorder characterized by motor neuron apoptosis and subsequent skeletal muscle atrophy caused by oxidative and nitrosative stress, mitochondrial dysfunction, and neuroinflammation. Anthocyanins are polyphenolic compounds found in berries that pos...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Koza, Lilia A., Winter, Aimee N., Holsopple, Jessica, Baybayon-Grandgeorge, Angela N., Pena, Claudia, Olson, Jeffrey R., Mazzarino, Randall C., Patterson, David, Linseman, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353311/
https://ncbi.nlm.nih.gov/pubmed/32570926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12061824
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