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Bromodomain-Containing Protein BRD4 Is Hyperphosphorylated in Mitosis
The epigenetic reader BRD4 binds acetylated histones and plays a central role in controlling cellular gene transcription and proliferation. Dysregulation of BRD4′s activity has been implicated in the pathogenesis of a wide variety of cancers. While blocking BRD4 interaction with acetylated histones...
Guardat en:
| Publicat a: | Cancers (Basel) |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7353023/ https://ncbi.nlm.nih.gov/pubmed/32575711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061637 |
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