PDX1 DNA Methylation Distinguishes Two Subtypes of Pancreatic Neuroendocrine Neoplasms with a Different Prognosis

DNA methylation is a crucial epigenetic mechanism for gene expression regulation and cell differentiation. Furthermore, it was found to play a major role in multiple pathological processes, including cancer. In pancreatic neuroendocrine neoplasms (PNENs), epigenetic deregulation is also considered t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Boons, Gitta, Vandamme, Timon, Ibrahim, Joe, Roeyen, Geert, Driessen, Ann, Peeters, Dieter, Lawrence, Ben, Print, Cristin, Peeters, Marc, Van Camp, Guy, Op de Beeck, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352978/
https://ncbi.nlm.nih.gov/pubmed/32512761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061461
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