Cell-Free DNA From Metastatic Pancreatic Neuroendocrine Tumor Patients Contains Tumor-Specific Mutations and Copy Number Variations

Background: Detection of tumor-specific alterations in cell-free DNA (cfDNA) has proven valuable as a liquid biopsy for several types of cancer. So far, use of cfDNA remains unexplored for pancreatic neuroendocrine tumor (PNET) patients. Methods: From 10 PNET patients, fresh frozen tumor tissue, buf...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Boons, Gitta, Vandamme, Timon, Peeters, Marc, Beyens, Matthias, Driessen, Ann, Janssens, Katrien, Zwaenepoel, Karen, Roeyen, Geert, Van Camp, Guy, Op de Beeck, Ken
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221938/
https://ncbi.nlm.nih.gov/pubmed/30443491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00467
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