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Update on GNA Alterations in Cancer: Implications for Uveal Melanoma Treatment

Tumorigenesis is correlated with abnormal expression and activity of G protein-coupled receptors (GPCRs) and associated G proteins. Oncogenic mutations in both GPCRs and G proteins (GNAS, GNAQ or GNA11) encoding genes have been identified in a significant number of tumors. Interestingly, uveal melan...

詳細記述

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Larribère, Lionel, Utikal, Jochen
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352965/
https://ncbi.nlm.nih.gov/pubmed/32532044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061524
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