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STAT3 Relays a Differential Response to Melanoma-Associated NRAS Mutations

Melanoma patients carrying an oncogenic NRAS mutation represent 20% of all cases and present worse survival, relapse rate and therapy response than patients with wild type NRAS or with BRAF mutations. Nevertheless, no efficient targeted therapy has emerged so far for this group of patients in compar...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kim, James, Novak, Daniel, Sachpekidis, Christos, Utikal, Jochen, Larribère, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016650/
https://ncbi.nlm.nih.gov/pubmed/31906480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010119
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