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Sorafenib Resistance in Hepatocellular Carcinoma: The Relevance of Genetic Heterogeneity

Despite advances in biomedicine, the incidence and the mortality of hepatocellular carcinoma (HCC) remain high. The majority of HCC cases are diagnosed in later stages leading to the less than optimal outcome of the treatments. Molecular targeted therapy with sorafenib, a dual-target inhibitor targe...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Cabral, Loraine Kay D., Tiribelli, Claudio, Sukowati, Caecilia H. C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352671/
https://ncbi.nlm.nih.gov/pubmed/32549224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061576
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