Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress

Background: Cisplatin (CDDP) is commonly utilized in the treatment of advanced solid tumors including head and neck squamous cell carcinoma (HNSCC). Cisplatin response remains highly variable among individual tumors and development of cisplatin resistance is common. We hypothesized that development...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Yu, Wangjie, Chen, Yunyun, Putluri, Nagireddy, Coarfa, Cristian, Robertson, Matthew J., Putluri, Vasanta, Stossi, Fabio, Dubrulle, Julien, Mancini, Michael A., Pang, Jonathan C., Nguyen, Trung, Baluya, Dodge, Myers, Jeffrey N., Lai, Stephen Y., Sandulache, Vlad C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352569/
https://ncbi.nlm.nih.gov/pubmed/32599707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061670
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