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Maackiain Ameliorates 6-Hydroxydopamine and SNCA Pathologies by Modulating the PINK1/Parkin Pathway in Models of Parkinson’s Disease in Caenorhabditis elegans and the SH-SY5Y Cell Line

The movement disorder Parkinson’s disease (PD) is the second most frequently diagnosed neurodegenerative disease, and is associated with aging, the environment, and genetic factors. The intracellular aggregation of α-synuclein and the loss of dopaminergic neurons in the substantia nigra pars compact...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Tsai, Rong-Tzong, Tsai, Chia-Wen, Liu, Shih-Ping, Gao, Jia-Xin, Kuo, Yun-Hua, Chao, Pei-Min, Hung, Huey-Shan, Shyu, Woei-Cherng, Lin, Shinn-Zong, Fu, Ru-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352553/
https://ncbi.nlm.nih.gov/pubmed/32585871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124455
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