Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma

Background: Predictive biomarkers of response to chemotherapy plus antiangiogenic for metastatic colorectal cancer (mCRC) are lacking. The objective of this study was to test the prognostic role of splenomegaly on baseline CT scan. Methods: This study is a sub-study of PRODIGE-9 study, which include...

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Udgivet i:Cancers (Basel)
Main Authors: Niogret, Julie, Limagne, Emeric, Thibaudin, Marion, Blanc, Julie, Bertaut, Aurelie, Le Malicot, Karine, Rinaldi, Yves, Caroli-Bosc, François-Xavier, Audemar, Franck, Nguyen, Suzanne, Sarda, Corinne, Lombard-Bohas, Catherine, Locher, Christophe, Carreiro, Miguel, Legoux, Jean-Louis, Etienne, Pierre-Luc, Baconnier, Mathieu, Porneuf, Marc, Aparicio, Thomas, Ghiringhelli, Francois
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352427/
https://ncbi.nlm.nih.gov/pubmed/32486421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061429
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