Non-Anticoagulant Heparan Sulfate from the Ascidian Phallusia nigra Prevents Colon Carcinoma Metastasis in Mice by Disrupting Platelet-Tumor Cell Interaction

Although metastasis is the primary cause of death in patients with malignant solid tumors, efficient anti-metastatic therapies are not clinically available currently. Sulfated glycosaminoglycans from marine sources have shown promising pharmacological effects, acting on different steps of the metast...

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Silva, Christiane F. S., Motta, Juliana M., Teixeira, Felipe C. O. B., Gomes, Angélica M., Vilanova, Eduardo, Kozlowski, Eliene O., Borsig, Lubor, Pavão, Mauro S. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352385/
https://ncbi.nlm.nih.gov/pubmed/32466418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061353
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