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Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition

Resistance to chemotherapeutics and targeted drugs is one of the main problems in successful cancer therapy. Various mechanisms have been identified to contribute to drug resistance. One of those mechanisms is lysosome-mediated drug resistance. Lysosomes have been shown to trap certain hydrophobic w...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Hraběta, Jan, Belhajová, Marie, Šubrtová, Hana, Merlos Rodrigo, Miguel Angel, Heger, Zbyněk, Eckschlager, Tomáš
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352242/
https://ncbi.nlm.nih.gov/pubmed/32575682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124392
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