Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition

Uveal melanoma (UM) is a rare tumor of the eye that leads to deadly metastases in about half of the patients. ADAM10 correlates with c-Met expression in UM and high levels of both molecules are related to the development of metastases. MiR122 and miR144 modulate ADAM10 and c-Met expression in differ...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Amaro, Adriana, Croce, Michela, Ferrini, Silvano, Barisione, Gaia, Gualco, Marina, Perri, Patrizia, Pfeffer, Ulrich, Jager, Martine J., Coupland, Sarah E., Mosci, Carlo, Filaci, Gilberto, Fabbi, Marina, Queirolo, Paola, Gangemi, Rosaria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352235/
https://ncbi.nlm.nih.gov/pubmed/32512881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061468
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