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Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies

Ubiquitin, a protein modifier that regulates diverse essential cellular processes, is also a component of the protein inclusions characteristic of many neurodegenerative disorders. In Alzheimer’s disease, the microtubule associated tau protein accumulates within damaged neurons in the form of cross-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Munari, Francesca, Barracchia, Carlo Giorgio, Parolini, Francesca, Tira, Roberto, Bubacco, Luigi, Assfalg, Michael, D’Onofrio, Mariapina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352214/
https://ncbi.nlm.nih.gov/pubmed/32575755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124400
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