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Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau

Background: The intrinsically disordered, amyloidogenic protein Tau associates with diverse classes of molecules, including proteins, nucleic acids, and lipids. Mounting evidence suggests that fatty acid molecules could play a role in the dysfunction of this protein, however, their interaction with...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Barracchia, Carlo Giorgio, Tira, Roberto, Parolini, Francesca, Munari, Francesca, Bubacco, Luigi, Spyroulias, Georgios A., D’Onofrio, Mariapina, Assfalg, Michael
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321374/
https://ncbi.nlm.nih.gov/pubmed/32545360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25112716
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