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Human organoids to model the developing human neocortex in health and disease

Rodent models have catalyzed major discoveries in the neocortex, a brain region unique to mammals. However, since the neocortex has expanded considerably in primates, employing rodent models has limitations. Human fetal brain tissue is a scarce resource with limitations for experimental manipulation...

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Bibliographic Details
Published in:Brain Res
Main Authors: Khakipoor, Shokoufeh, Crouch, Elizabeth E., Mayer, Simone
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352040/
https://ncbi.nlm.nih.gov/pubmed/32240655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2020.146803
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