Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1

Hepatic amebiasis, predominantly occurring in men, is a focal destruction of the liver due to the invading protozoan Entamoeba histolytica. Classical monocytes as well as testosterone are identified to have important functions for the development of hepatic amebiasis in mice, but a link between test...

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Udgivet i:Nat Commun
Main Authors: Sellau, Julie, Groneberg, Marie, Fehling, Helena, Thye, Thorsten, Hoenow, Stefan, Marggraff, Claudia, Weskamm, Marie, Hansen, Charlotte, Stanelle-Bertram, Stephanie, Kuehl, Svenja, Noll, Jill, Wolf, Vincent, Metwally, Nahla Galal, Hagen, Sven Hendrik, Dorn, Christoph, Wernecke, Julia, Ittrich, Harald, Tannich, Egbert, Jacobs, Thomas, Bruchhaus, Iris, Altfeld, Marcus, Lotter, Hannelore
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351718/
https://ncbi.nlm.nih.gov/pubmed/32651360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17260-y
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