Overexpression of Differentially Expressed Genes Identified in Non-pathogenic and Pathogenic Entamoeba histolytica Clones Allow Identification of New Pathogenicity Factors Involved in Amoebic Liver Abscess Formation

We here compared pathogenic (p) and non-pathogenic (np) isolates of Entamoeba histolytica to identify molecules involved in the ability of this parasite to induce amoebic liver abscess (ALA)-like lesions in two rodent models for the disease. We performed a comprehensive analysis of 12 clones (A1–A12...

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Pubblicato in:PLoS Pathog
Autori principali: Meyer, Martin, Fehling, Helena, Matthiesen, Jenny, Lorenzen, Stephan, Schuldt, Kathrin, Bernin, Hannah, Zaruba, Mareen, Lender, Corinna, Ernst, Thomas, Ittrich, Harald, Roeder, Thomas, Tannich, Egbert, Lotter, Hannelore, Bruchhaus, Iris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004846/
https://ncbi.nlm.nih.gov/pubmed/27575775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005853
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