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Harnessing the biology of IL-7 for therapeutic application
Interleukin-7 (IL-7) is required for T cell development and for maintaining and restoring homeostasis of mature T cells. IL-7 is a limiting resource under normal conditions, but it accumulates during lymphopaenia, leading to increased T cell proliferation. The administration of recombinant human IL-...
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| Veröffentlicht in: | Nat Rev Immunol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7351348/ https://ncbi.nlm.nih.gov/pubmed/21508983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2970 |
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